Open AccessCharacterization of Virus Replication, Pathogenesis, and Cytokine Responses in Syrian Hamsters Inoculated with SARS-CoV-2
Author(s) -
Shiu-Ju Yang,
Ting-Chun Wei,
Chih-Hao Hsu,
Sin-Ni Ho,
Chi-Yun Lai,
SuCheng Huang,
Yih-Yuan Chen,
ShihJen Liu,
Guann-Yi Yu,
Horng-Yunn Dou
Publication year - 2021
Publication title -
journal of inflammation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s323026
Subject(s) - immune system , mesocricetus , viral load , pathogenesis , cytokine , immunology , biology , virology , viral pathogenesis , virus , viral replication , coronavirus , hamster , medicine , pathology , endocrinology , infectious disease (medical specialty) , disease , covid-19
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus which caused a global respiratory disease pandemic beginning in December 2019. Understanding the pathogenesis of infection and the immune responses in a SARS-CoV-2-infected animal model is urgently needed for vaccine development.