Open AccessNecroptosis Underlies Neutrophilic Inflammation Associated with the Chronic Rhinosinusitis with Nasal Polyps (CRSwNP)
Author(s) -
Yadong Xie,
Min Li,
Kun Chen,
Haoxiang Zhu,
Min Tang,
Chun Zhou,
Yaoming Zheng,
Jing Wen,
Miaomiao Han,
Jia Zhang,
Keqing Zhao,
Hui Xiao,
Hua-Bin Li
Publication year - 2021
Publication title -
journal of inflammation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s322875
Subject(s) - necroptosis , nasal polyps , pyroptosis , proinflammatory cytokine , immunology , inflammation , chemokine , programmed cell death , medicine , eosinophil , tumor necrosis factor alpha , apoptosis , pathology , inflammasome , biology , biochemistry , asthma
Necroptosis is an inflammatory cell death associated with a variety of chronic diseases. Chronic rhinosinusitis with nasal polyps (CRSwNP) is a chronic inflammatory disease accompanied by eosinophil and neutrophil infiltration. The role of necroptosis in the pathogenesis of CRSwNP remains elusive.