Open AccessIdentification and Integrated Analysis of circRNA and miRNA of Radiation-Induced Lung Injury in a Mouse Model
Author(s) -
Yida Li,
Liang Zou,
Li Chu,
Luxi Ye,
Jianjiao Ni,
Xiao Chu,
Tiantian Guo,
Xi Yang,
Zhengfei Zhu
Publication year - 2021
Publication title -
journal of inflammation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s322736
Subject(s) - microrna , biology , signal transduction , microbiology and biotechnology , cancer research , receptor , chemokine , cell growth , gene , genetics
Radiation-induced lung injury (RILI) is a main threat to patients who received thoracic radiotherapy. Thus, understanding the molecular mechanism of RILI is of great importance. Circular RNAs (circRNAs) have been found to act as a regulator of multiple biological processes, and the circRNA-microRNA (miRNA)-mRNA axis could play an important role in the signaling pathway of many human diseases including radiation injury.