Open AccessAssessment of Pyroptosis-Related Indicators as Potential Biomarkers and Their Association with Severity in Patients with Liver Cirrhosis
Author(s) -
Ding Wang,
Xi Zhan,
Rui Wu,
Yan You,
Weixian Chen,
Liang Duan
Publication year - 2021
Publication title -
journal of inflammation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s319213
Subject(s) - cirrhosis , pyroptosis , medicine , ascites , gastroenterology , liver disease , chronic liver disease , disease , inflammation , inflammasome
The diagnosis and management of liver cirrhosis remain challenging due to its diverse clinical manifestations and elusive severity evaluation. Pyroptosis, an identified inflammatory form of cell death, has recently been reported to participate in cirrhosis development. Nonetheless, the clinical significance of pyroptosis in liver cirrhosis remains largely unexplored.