Open AccessThe Combination of Stromal Vascular Fraction Cells and Platelet-Rich Plasma Reduces Malondialdehyde and Nitric Oxide Levels in Deep Dermal Burn Injury
Author(s) -
Fonny Josh,
Tomie Hermawan Soekamto,
Januar Rizky Adriani,
Billy Jonatan,
Hiroshi Mizuno,
Muhammad Faruk
Publication year - 2021
Publication title -
journal of inflammation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s318055
Subject(s) - malondialdehyde , vaseline , platelet rich plasma , nitric oxide , platelet , chemistry , medicine , pharmacology , wound healing , immunology , oxidative stress
Thermal burns release reactive oxygen species, which cause profound systemic and local changes. Stromal vascular fraction cells (SVFs) combined with platelet-rich plasma accelerate burn wound healing. This study investigated the effect of a combination of locally injected SVFs and PRP on malondialdehyde (MDA) and nitric oxide (NO) serum and tissue levels in a deep dermal burn model in Wistar rats.