Open AccessSymmetric Dimethylarginine is Altered in Patients After Myocardial Infarction and Predicts Adverse Outcomes
Author(s) -
Aleksandra Gąsecka,
Piotr Szwed,
Karolina Jasińska,
Oliwia Fidali,
Aleksandra Kłębukowska,
Ceren Eyileten,
Marek Postuła,
Łukasz Szarpak,
Tomasz Mazurek,
Grzegorz Opolski,
Krzysztof J. Filipiak,
Marcin Ufnal
Publication year - 2021
Publication title -
journal of inflammation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s316078
Subject(s) - mace , myocardial infarction , medicine , cardiology , nitric oxide , asymmetric dimethylarginine , arginine , endothelium , chemistry , biochemistry , amino acid , conventional pci
Acute myocardial infarction (AMI) is the leading cause of morbidity and mortality worldwide. Damage to the endothelium is the earliest event in atherothrombosis, including AMI. Nitric oxide (NO), an endothelium-derived compound, protects the vasculature from damage. This study evaluated whether an association exists between plasma concentration of endogenous NO-related pathway metabolites linked to AMI and major adverse cardiovascular events (MACE) after AMI.