
Exploration of Potential Molecular Targets of Dexmedetomidine in the Intestinal Repair of Burnt Rats
Author(s) -
Chao Qin,
Yi Jiang,
Mingdong Yu,
Yingxue Bian,
Yonghao Yu
Publication year - 2021
Publication title -
journal of inflammation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s315952
Subject(s) - diamine oxidase , dexmedetomidine , kegg , intestinal permeability , pharmacology , dextran , medicine , endocrinology , gene , chemistry , gene expression , gene ontology , biochemistry , enzyme , sedation
More and more burn survivors were suffering from varying degrees of damage to the intestinal barrier. Dexmedetomidine (Dex) was frequently used as sedative in more cases, but it was found to have repair effect on intestinal barrier dysfunction recently. This study aimed to explore the potential specific targets of Dex in intestinal barrier repair in burn rats model.