Open AccessTranscriptome-Wide Analysis to Identify the Inflammatory Role of lncRNA Neat1 in Experimental Ischemic Stroke
Author(s) -
Fa Jin,
Weiyang Ou,
Boyang Wei,
Haiyan Fan,
Chengcong Wei,
Dazhao Fang,
Guangxu Li,
Wenchao Li,
Jiahui Liu,
Lei Jin,
Xiaofu He,
Chuanzhi Duan
Publication year - 2021
Publication title -
journal of inflammation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s315281
Subject(s) - neuroinflammation , proinflammatory cytokine , gene knockdown , microglia , kegg , inflammation , transcriptome , biology , immune system , gene expression , immunology , gene , biochemistry
Ischemic stroke is one of the leading causes of mortality and disability worldwide. Following stroke, there is secondary neuroinflammation that promotes further injury. Identifying the long non-coding RNA (lncRNA) involved in neuroinflammation after cerebral ischemic stroke will promote the discovery of potential therapeutic targets.