Open AccessLocalized and Systemic Inflammatory Mediators in a Murine Acute Mastitis Model
Author(s) -
Misako Takashima,
Christian Lalonde,
Laura Ashley Olszanski,
FengQi Zhao
Publication year - 2021
Publication title -
journal of inflammation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s313799
Subject(s) - lipopolysaccharide , cytokine , endocrinology , tumor necrosis factor alpha , nitric oxide , medicine , monocyte , proinflammatory cytokine , inflammation , immunology , chemistry , biology , andrology
Milk depression is the major driver of economic loss due to mastitis in dairy animals. The aim of this study was to identify potential mediators of milk depression by investigating the local and systemic changes in gene expression or cytokine production during endotoxin challenge of the mammary gland in a mouse model.