Open AccessQuercetin Alleviates Osteoarthritis Progression in Rats by Suppressing Inflammation and Apoptosis via Inhibition of IRAK1/NLRP3 Signaling
Author(s) -
Wenjun Li,
Yeyang Wang,
Yaqin Tang,
Hanyu Lu,
Yong Qi,
Guitao Li,
Hebei He,
Fanglian Lu,
Yixin Yang,
Han Sun
Publication year - 2021
Publication title -
journal of inflammation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s311924
Subject(s) - apoptosis , inflammation , chondrocyte , quercetin , blot , cartilage , osteoarthritis , flow cytometry , cancer research , chemistry , pharmacology , microbiology and biotechnology , immunology , medicine , in vitro , biology , pathology , biochemistry , anatomy , alternative medicine , gene , antioxidant
Quercetin was recently reported to help protect against osteoarthritis (OA) progression, but the molecular mechanism for that protective affect remains unclear.