Open AccessInsights into the Implications of Coexisting Type 2 Inflammatory Diseases
Author(s) -
Justin P. McCormick,
Jivianne T. Lee
Publication year - 2021
Publication title -
journal of inflammation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s311640
Subject(s) - eosinophilic esophagitis , atopic dermatitis , medicine , asthma , chronic rhinosinusitis , inflammation , pathogenesis , immunology , disease , eosinophilic , nerd , dermatology , gerd , pathology , reflux
The role of type 2 inflammation in the pathogenesis of certain human diseases is an area of active investigation. Certain asthma, atopic dermatitis, eosinophilic esophagitis, and chronic rhinosinusitis phenotypes are characterized by a Th2 predominant inflammatory pathway and are frequently associated with comorbid conditions in patients. The purpose of this article is to review the evidence behind concurrent Th2-mediated diseases and explore how the presence of these comorbid conditions affect patient and disease outcomes.