Open AccessPrognostic Significance of Tumor-Associated Macrophages in Chondroblastoma and Their Association with Response to Adjuvant Radiotherapy
Author(s) -
Bowen Zheng,
Minliang Yang,
Wei Huang,
Bo-Yv Zheng,
Tao-Lan Zhang,
Jing Li,
Guohua Lv,
Yongping Yan,
Ming-Xiang Zou
Publication year - 2021
Publication title -
journal of inflammation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s308707
Subject(s) - medicine , chondroblastoma , radiation therapy , oncology , adjuvant , pathology
Chondroblastoma (CB) is a rare and locally growing cartilage-derived tumor. Currently, clinical implications of tumor-associated macrophages (TAMs) in CB remain unclear. In this study, we sought to analyze the relationship between TAM parameters (including densities of CD68+ and CD163+ cells as well as the CD163+/CD68+ ratio) and clinicopathological characteristics and survival of patients.