Open AccessIntegrated Systems Pharmacology and Surface Plasmon Resonance Approaches to Reveal the Synergistic Effect of Multiple Components of Gu-Ben-Ke-Chuan Decoction on Chronic Bronchitis
Author(s) -
Zhiqiang Luo,
Guohua Yang,
Wubin Wang,
Rui Sun,
Binbin Zhang,
Jing Wang,
Jing Liu,
Shan Gao,
Peng Wang,
Yuanyuan Shi
Publication year - 2021
Publication title -
journal of inflammation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s303530
Subject(s) - chemistry , chronic bronchitis , surface plasmon resonance , decoction , pharmacology , docking (animal) , curcumin , tumor necrosis factor alpha , mechanism of action , orbitrap , biochemistry , mass spectrometry , chromatography , traditional medicine , biology , medicine , immunology , nanotechnology , materials science , nursing , nanoparticle , in vitro
Gu-Ben-Ke-Chuan (GBKC) decoction, a well-known prescription composed of seven herbs, has been widely used for treating chronic bronchitis (CB). However, the pharmacological constituents of GBKC and the underlying mechanisms by which these components act on CB remain unclear.