Open AccessStudy of the Expression of Inflammatory Factors IL-4, IL-6, IL-10, and IL-17 in Liver Failure Complicated by Coagulation Dysfunction and Sepsis
Author(s) -
Lei Li,
Ling Chen,
FangYue Lin,
Jinsong Mu,
Dan Wang,
Wei Zhang,
Lai Mi,
Yue Qin,
Yue-Su Zhou
Publication year - 2021
Publication title -
journal of inflammation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s302975
Subject(s) - medicine , sepsis , cirrhosis , gastroenterology , coagulation , interleukin , interleukin 6 , inflammation , immunology , cytokine
The present study aims to investigate the cytokines interleukin (IL)-4, IL-6, IL-10, and IL-17 in the peripheral blood of patients with acute-on-chronic liver failure combined with sepsis, patients with acute-on-chronic liver failure, and patients with liver cirrhosis; to investigate the changes in the levels of inflammatory factors in cases of coagulation dysfunction in liver failure combined with sepsis; and to discover more typical inflammatory factors for further evaluation by functional experiments.