Open AccessGinkgo biloba Extract 50 (GBE50) Ameliorates Insulin Resistance, Hepatic Steatosis and Liver Injury in High Fat Diet-Fed Mice
Author(s) -
Liu Li,
Li Yang,
Feng Yang,
Xin-Lan Zhao,
Sheng-Jiang Xue,
Fanghua Gong
Publication year - 2021
Publication title -
journal of inflammation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s302934
Subject(s) - insulin resistance , steatosis , fatty liver , medicine , liver injury , endocrinology , ginkgo biloba , nonalcoholic fatty liver disease , lipid metabolism , insulin , pharmacology , disease
Ginkgo biloba extract 50 (GBE50) has a variety of pharmacological functions such as anti-inflammatory, antioxidant and maintenance of glucose and lipid metabolism homeostasis. However, the therapeutic effects and mechanisms of GBE50 on non-alcoholic fatty liver disease (NAFLD) remain unknown. Therefore, in this study, we evaluated the therapeutic effects of GBE50 in NAFLD by using a high-fat diet (HFD) mice model.