Open AccessIsovitexin Depresses Osteoarthritis Progression via the Nrf2/NF-κB Pathway: An in vitro Study
Author(s) -
Xiaofen Hu,
Ruijie Li,
Ming Sun,
Ying Kong,
Haifeng Zhu,
Fujiang Wang,
Quanqing Wan
Publication year - 2021
Publication title -
journal of inflammation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s299557
Subject(s) - western blot , nf κb , osteoarthritis , inflammation , chemistry , in vitro , small interfering rna , extracellular matrix , microbiology and biotechnology , chondrocyte , isovitexin , signal transduction , cancer research , biology , immunology , transfection , medicine , biochemistry , gene , pathology , flavonoid , vitexin , antioxidant , alternative medicine
Osteoarthritis (OA) is a multifactorial joint disease and inflammatory processes contribute to joint destruction. Isovitexin (IVX) is a flavone component found in passion flower, Cannabis and, and the palm that is known for its anti-inflammatory properties.