Open AccessTripterygium wilfordii Polyglycoside Ameliorated TNBS-Induced Colitis in Rats via Regulating Th17/Treg Balance in Intestinal Mucosa
Author(s) -
Cui Zhang,
Jingyi Ju,
Xiaohan Wu,
Jiaolan Yang,
Yang Qi,
Chunlu Liu,
Liang Chen,
Xiaomin Sun
Publication year - 2021
Publication title -
journal of inflammation research
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s293961
Subject(s) - foxp3 , il 2 receptor , immunology , ulcerative colitis , spleen , colitis , medicine , regulatory t cell , intestinal mucosa , immune system , inflammatory bowel disease , flow cytometry , rar related orphan receptor gamma , inflammation , t cell , disease
To investigate the therapeutic effect of Tripterygium wilfordii polyglycoside (TWP), a derivative from a Chinese traditional herb, on 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced colitis, in a model for inflammatory bowel disease (IBD) in rats.