Open AccessThe Pulsatile Modification Improves Hemodynamics and Attenuates Inflammatory Responses in Extracorporeal Membrane Oxygenation
Author(s) -
Guanhua Li,
Jianfeng Zeng,
Zhaoyuan Liu,
Yu Zhang,
Xiaoping Fan
Publication year - 2021
Publication title -
journal of inflammation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s292543
Subject(s) - pulsatile flow , hemodynamics , medicine , extracorporeal membrane oxygenation , extracorporeal , membrane oxygenator , microcirculation , perfusion , anesthesia , cardiology
COVID-19 is still a worldwide pandemic and extracorporeal membrane oxygenation (ECMO) is vital for extremely critical COVID-19 patients. Pulsatile flow impacts greatly on organ function and microcirculation, however, the effects of pulsatile flow on hemodynamics and inflammatory responses during ECMO are unknown. An in vivo study was launched aiming at comparing the two perfusion modes in ECMO.