Open AccessCathelicidin – A Novel Potential Marker of Pediatric Inflammatory Bowel Disease
Author(s) -
Paulina Krawiec,
Elżbieta Pac-Kożuchowska
Publication year - 2021
Publication title -
journal of inflammation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s288742
Subject(s) - cathelicidin , ulcerative colitis , calprotectin , inflammatory bowel disease , medicine , gastroenterology , immunology , erythrocyte sedimentation rate , colitis , biomarker , disease , immune system , biology , innate immune system , biochemistry
Cathelicidin is a multifunctional host defense peptide which may also exert pro-inflammatory signals and contribute to the development of autoimmune disorders. We aimed to assess serum concentration of cathelicidin in children with inflammatory bowel disease (IBD) compared to healthy controls and to evaluate its relationship with disease activity and phenotype.