Open Access<p>Comparative Effects of Dexamethasone and Meloxicam on Magnitude of the Acute Inflammatory Response Induced by <em>Escherichia coli</em> Lipopolysaccharide in Broiler Chickens</p>
Author(s) -
Mohadeseh Manzari Tavakoli,
Bahman Abdi-Hachesoo,
Saeed Nazifi,
Najmeh Mosleh,
Seyedeh Alemeh Hosseinian,
Peyman Nakhaee
Publication year - 2020
Publication title -
journal of inflammation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s258328
Subject(s) - meloxicam , lipopolysaccharide , dexamethasone , broiler , acute phase protein , medicine , sialic acid , piroxicam , pharmacology , endocrinology , inflammation , chemistry , biology , biochemistry , zoology , alternative medicine , pathology
Dexamethasone has been widely used to treat acute inflammatory diseases and endotoxic shocks in animal models. Meloxicam is one of the most commonly used anti-inflammatory agents in avian species. However, little is known about the effects of dexamethasone and meloxicam on lipopolysaccharide (LPS)-induced acute inflammatory response in birds. In the present study, LPS-challenged broiler chickens were used to investigate the comparative protective effects of meloxicam and dexamethasone on LPS-induced acute inflammatory responses.