Open Access<p>MicroRNA-21-3p Engineered Umbilical Cord Stem Cell-Derived Exosomes Inhibit Tendon Adhesion</p>
Author(s) -
Zhewei Yao,
Juehong Li,
Xu Wang,
Siyun Peng,
Jiexin Ning,
Yun Qian,
Cunyi Fan
Publication year - 2020
Publication title -
journal of inflammation research
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 33
ISSN - 1178-7031
DOI - 10.2147/jir.s254879
Subject(s) - adhesion , microbiology and biotechnology , microrna , tendon , cell adhesion , microvesicles , mesenchymal stem cell , fibroblast , fibrosis , chemistry , cancer research , in vitro , biology , medicine , pathology , anatomy , biochemistry , gene , organic chemistry
As a common complication of tendon injury, tendon adhesion is an unresolved problem in clinical work. The aim of this study was to investigate whether human umbilical cord mesenchymal stem cell-derived exosomes (HUMSC-Exos), one of the most promising new-generation cell-free therapeutic agents, can improve tendon adhesion and explore potential-related mechanisms.