Open AccessNonsynonymous C1653T Mutation of Hepatitis B Virus X Gene Enhances Malignancy of Hepatocellular Carcinoma Cells
Author(s) -
Cuifang Zhang,
Ying Xie,
Ruixue Lai,
Jianhua Wu,
Zhanjun Guo
Publication year - 2022
Publication title -
journal of hepatocellular carcinoma
Language(s) - English
Resource type - Journals
ISSN - 2253-5969
DOI - 10.2147/jhc.s348690
Subject(s) - hepatocellular carcinoma , virology , nonsynonymous substitution , mutation , malignancy , hepatitis b virus , gene , hepatitis c virus , virus , biology , gene mutation , cancer research , medicine , genetics , genome
Functional analysis was performed to elucidate the mechanism by which hepatocellular carcinoma (HCC) outcome-associated mutation in the hepatitis B virus X ( HBx ) gene modifies the HCC process.