Open AccessIntraarterial Lidocaine Administration for Pain Control by Water-in-Oil Technique in Transarterial Chemoembolization: in vivo and Randomized Clinical Trial
Author(s) -
Lizhou Wang,
Xiaoxia Hu,
Xiangchun Shen,
Tiancheng Wang,
Shi Zhou
Publication year - 2021
Publication title -
journal of hepatocellular carcinoma
Language(s) - English
Resource type - Journals
ISSN - 2253-5969
DOI - 10.2147/jhc.s331779
Subject(s) - lidocaine , medicine , epirubicin , lipiodol , anesthesia , hepatocellular carcinoma , visual analogue scale , bolus (digestion) , randomized controlled trial , adverse effect , in vivo , surgery , chemotherapy , microbiology and biotechnology , biology , cyclophosphamide
To investigate the sustained release of lidocaine from a lidocaine-epirubicin-lipiodol emulsion created by water-in-oil (W/O) technique in vivo and evaluate the efficacy and safety of intraarterial lidocaine administration for intra- and postoperative pain control in transarterial chemoembolization (TACE) for hepatocellular carcinoma (HCC).