Open AccessResponse Stratification in the First-Line Combined Immunotherapy of Hepatocellular Carcinoma at Genomic, Transcriptional and Immune Repertoire Levels
Author(s) -
Jiamin Cheng,
Yinyin Li,
Xiaohui Wang,
Dong Zheng,
Yan Chen,
Rui Zhang,
Jieting Huang,
Xin Jin,
Jianfei Yao,
Aifang Ge,
Lele Song,
Yinying Lu,
Zhen Zeng
Publication year - 2021
Publication title -
journal of hepatocellular carcinoma
Language(s) - English
Resource type - Journals
ISSN - 2253-5969
DOI - 10.2147/jhc.s326356
Subject(s) - immunotherapy , hepatocellular carcinoma , cancer research , biology , immune system , cdkn2a , oncology , immunology , medicine , cancer
Immunotherapy combined with VEGF inhibitor has become the new first-line therapy for advanced or metastatic hepatocellular carcinoma (HCC). However, the biomarkers for response and prognosis stratification of HCC first-line combined immunotherapy have not been clarified.