Open Access<p>Development and Verification of the Hypoxia-Related and Immune-Associated Prognosis Signature for Hepatocellular Carcinoma</p>
Author(s) -
Bo Hu,
Xiaobo Yang,
Xinting Sang
Publication year - 2020
Publication title -
journal of hepatocellular carcinoma
Language(s) - English
Resource type - Journals
ISSN - 2253-5969
DOI - 10.2147/jhc.s272109
Subject(s) - hepatocellular carcinoma , immune system , hypoxia (environmental) , cohort , proportional hazards model , oncology , gene signature , transcriptome , lasso (programming language) , medicine , gene , immunology , biology , gene expression , genetics , chemistry , organic chemistry , oxygen , world wide web , computer science
It has been widely suggested that the association of hypoxia with the immune status within the microenvironment of hepatocellular carcinoma (HCC) is of great clinical significance. The present work was carried out aiming to establish the hypoxia-related and immune-associated gene signature to stratify the risks in HCC.