Open AccessAntidiabetic Activity of Hydromethanolic Extract of Crude Dorstenia barnimiana Root: Validation of In Vitro and In Vivo Antidiabetic and Antidyslipidemic Activity
Author(s) -
Woretaw Sisay,
Y Andargie,
Mulugeta Molla
Publication year - 2022
Publication title -
journal of experimental pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.555
H-Index - 12
ISSN - 1179-1454
DOI - 10.2147/jep.s343735
Subject(s) - glibenclamide , in vivo , distilled water , diabetes mellitus , in vitro , streptozotocin , traditional medicine , amylase , chemistry , pharmacology , medicine , endocrinology , biochemistry , biology , enzyme , microbiology and biotechnology , chromatography
Despite modern therapeutic armamentaria, DM remains a 21st-century public health menace. Novel phytomedicines are a rapidly expanding focus of research. The juice of Dorstenia barnimiana roots has long been used for the treatment of diabetes mellitus in traditional Ethiopian medicine, but its efficacy has not been supported by in vitro or in vivo scientific study. To investigate this, the present work was performed.