Open AccessEvaluation of the Antimalarial Activity of Ethanol Extracts of the Leaves of Three Plant Species Collected from Yayu Coffee Forest Biosphere Reserve, Southwest Ethiopia
Author(s) -
Solomon Yeshanew,
Worke Gete,
Desalegn Chilo
Publication year - 2021
Publication title -
journal of experimental pharmacology
Language(s) - English
Resource type - Journals
ISSN - 1179-1454
DOI - 10.2147/jep.s304933
Subject(s) - parasitemia , vernonia amygdalina , phytochemical , plasmodium berghei , traditional medicine , pharmacology , acute toxicity , biology , chloroquine , in vivo , dose dependence , toxicity , malaria , toxicology , medicine , plasmodium falciparum , microbiology and biotechnology , immunology , endocrinology
In the attempt of searching for potential plant derived antimalarial medicines, the aim of the present study was to examine In vivo antimalarial efficacy of crude ethanol extracts of the leaves of Croton macrostachyus, Ruta chalepensis and Vernonia amygdalina using chloroquine (CQ) sensitive strains of Plasmodium berghei in Swiss albino mice.