Open AccessApplication of Topical Sucralfate and Topical Platelet-Rich Plasma Improves Wound Healing in Diabetic Ulcer Rats Wound Model
Author(s) -
Renni Yuniati,
Innelya Innelya,
Arti Rachmawati,
Harold Jefferson Matthew Charlex,
Alfi Rahmatika,
Matthew Brian Khrisna,
Farmaditya Ep Mundhofir,
K Heri Nugroho Hario Seno,
Tri Nur Kristina
Publication year - 2021
Publication title -
journal of experimental pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.555
H-Index - 12
ISSN - 1179-1454
DOI - 10.2147/jep.s296767
Subject(s) - sucralfate , medicine , wound healing , platelet , platelet rich plasma , growth factor , diabetes mellitus , vascular endothelial growth factor , gastroenterology , surgery , endocrinology , receptor , vegf receptors
One of the most serious and devastating complications of diabetes mellitus is diabetic ulcers. They are difficult to treat and often result in limb loss. Topical sucralfate and platelet-rich plasma have the potential to improve the healing outcomes of chronic ulcers, including diabetic ulcers. This research aims to determine the effectiveness of sucralfate and platelet-rich plasma therapy for the improvement of diabetic ulcer wound healing.