Open Access<p>In vitro Antioxidant and in vivo Hepatoprotective Activities of Root Bark Extract and Solvent Fractions of <em>Croton macrostachyus</em> Hochst. Ex Del. (<em>Euphorbiaceae</em>) on Paracetamol-Induced Liver Damage in Mice</p>
Author(s) -
Gebrehiwot Gebremedhin Tafere,
Kald Beshir Tuem,
Abadi Kahsu Gebre,
Rajkapoor Balasubramaniam
Publication year - 2020
Publication title -
journal of experimental pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.555
H-Index - 12
ISSN - 1179-1454
DOI - 10.2147/jep.s259081
Subject(s) - antioxidant , traditional medicine , chemistry , chloroform , bilirubin , bark (sound) , dpph , croton , in vivo , pharmacology , biochemistry , biology , medicine , chromatography , microbiology and biotechnology , ecology
Liver disease is a major public health threat, particularly in developing countries. Several medicinal plants and formulations have been claimed to have liver protective activities. The present study aimed to evaluate in vitro antioxidant and in vivo hepatoprotective activities of root bark extracts of Croton macrostachyus (Euphorbiaceae).