Open Access<p>In vivo Hepatoprotective and in vitro Radical Scavenging Activities of Extracts of <em>Rumex abyssinicus</em> Jacq. Rhizome</p>
Author(s) -
Betelhem Anteneh Adamu,
Yohannes Kelifa Emiru,
Biruk Sintayehu,
Ephrem Mebrhatu Araya,
Gomathi Periasamy,
Mebrahtom Gebrelibanos Hiben
Publication year - 2020
Publication title -
journal of experimental pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.555
H-Index - 12
ISSN - 1179-1454
DOI - 10.2147/jep.s258566
Subject(s) - carbon tetrachloride , hepatoprotection , rhizome , in vivo , ccl4 , pharmacology , dpph , traditional medicine , chemistry , liver injury , hepatotoxin , antioxidant , medicine , biology , enzyme , biochemistry , toxicity , microbiology and biotechnology , glutathione , organic chemistry
Liver diseases contribute a prominent global burden of mortality and morbidity. The current therapies of liver diseases have numerous limitations including severe adverse effects. This denotes that new more effective, safer, and cheaper drugs are required and medicinal plants used in traditional medicines often offer ideal opportunities. Accordingly, the present study aimed to evaluate the in vivo hepatoprotective and in vitro radical scavenging activities of dried rhizome extracts of Rumex abyssinicus ( R. abyssinicus ), which is traditionally claimed to provide hepatoprotection.