Open Access<p>Evaluation of Hepatoprotective Activity of the Crude Extract and Solvent Fractions of <em>Clutia abyssinica</em> (<em>Euphorbiaceae</em>) Leaf Against CCl<sub>4</sub>-Induced Hepatotoxicity in Mice</p>
Author(s) -
Birhanu Geta Meharie,
Gedefaw Getnet Amare,
Yaschilal Muche Belayneh
Publication year - 2020
Publication title -
journal of experimental pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.555
H-Index - 12
ISSN - 1179-1454
DOI - 10.2147/jep.s248677
Subject(s) - carbon tetrachloride , maceration (sewage) , distilled water , chemistry , traditional medicine , albumin , solvent , bilirubin , liver function , chloroform , ccl4 , biochemistry , alkaline phosphatase , chromatography , pharmacology , biology , medicine , enzyme , organic chemistry , materials science , composite material
Liver is a vital organ that plays a major role in the elimination of xenobiotics from the body. Diseases that affect the liver become major health problems and challenge health-care professionals as well as the pharmaceutical industry. Since the conventional treatment of liver diseases is associated with a wide range of adverse effects, botanical agents are commonly used. Among these agents, Clutia abyssinica is the most widely used herb in Ethiopian traditional medicine.