Open AccessABO and Rh Antigen Distribution Among Pregnant Women in South Western Uganda
Author(s) -
Yona Mbalibulha,
Bernard Natukunda,
Okwi Andrew Livex,
Sam Oge,
Joan N. Kalyango,
Kajja Isaac
Publication year - 2022
Publication title -
journal of blood medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.676
H-Index - 18
ISSN - 1179-2736
DOI - 10.2147/jbm.s360769
Subject(s) - abo blood group system , medicine , rh blood group system , antigen , haemolytic disease , blood grouping , h antigen , agglutination (biology) , abo incompatibility , blood transfusion , immunology , obstetrics , fetus , pregnancy , antibody , biology , genetics
ABO and Rh are the major blood group systems in Transfusion Medicine, the ABO system based on two red cell antigens (A, B) while the Rh has about 50 antigens of which five are highly clinically significant (D, C, c , E, e ). These vary among races and ethnic groups. Blood type phenotype incompatibility between mother and fetus may result in antigen mismatch, triggering alloimmunization, and thus causing hemolytic transfusion reaction (HTR), which results in hemolytic disease of fetus and newborn (HDFN). This study aimed to determine the frequencies of ABO and rhesus blood group antigen in the pregnant women in South Western Uganda.