Open AccessA Prospective Observational Study of Antihemophilic Factor (Recombinant) Prophylaxis Related to Physical Activity Levels in Patients with Hemophilia A in the United States (SPACE)
Author(s) -
Barbara A. Konkle,
Doris Quon,
Leslie Raffini,
Michael Recht,
Vlad C. Radulescu,
Shan L. Carpenter,
Amy L. Dunn,
Mei Lü,
Maureen Watt
Publication year - 2021
Publication title -
journal of blood medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.676
H-Index - 18
ISSN - 1179-2736
DOI - 10.2147/jbm.s327180
Subject(s) - medicine , observational study , physical activity , odds ratio , prospective cohort study , recombinant factor viia , physical therapy
High collision-risk physical activity can increase bleeding risk in people with hemophilia A, as can increasing the time between factor VIII (FVIII) administration and physical activity. FVIII prophylaxis may be tailored to planned activities to prevent activity-related bleeding.