Open AccessPossible Role of CD11a in Primary Immune Thrombocytopenia Patients on Immunosuppressive Therapy
Author(s) -
Muhamad R. Abdel Hameed,
Howiada A Nafady,
Mona Ibrahim Mostafa,
Douaa Sayed,
Ahmad A Obiedallah
Publication year - 2021
Publication title -
journal of blood medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.676
H-Index - 18
ISSN - 1179-2736
DOI - 10.2147/jbm.s300717
Subject(s) - medicine , immune thrombocytopenia , intensive care medicine , immunology , antibody
Immune thrombocytopenia (ITP) is one of the autoimmune diseases that presented by thrombocytopenia and increased risk of bleeding. Etiology of immune thrombocytopenia (ITP) is very complex. Lymphocyte function associated antigen-1 (LFA-1) plays important role in ITP. The aim of this study was evaluation of expression of CD11a on lymphocytes to explore its possible role in primary ITP patients also, regarding severity and response to immunosuppressive treatment.