Open AccessDiagnostic Value of Neutrophil Lymphocyte Ratio and D-Dimer as Biological Markers of Deep Vein Thrombosis in Patients Presenting with Unilateral Limb Edema
Author(s) -
Ikhwan Rinaldi,
Rachmat Hamonangan,
Mohammad Azizi,
Rahmat Cahyanur,
Fadila Wirawan,
Atikah Isna Fatya,
Ageng Budiananti,
Kevin Winston
Publication year - 2021
Publication title -
journal of blood medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.676
H-Index - 18
ISSN - 1179-2736
DOI - 10.2147/jbm.s291226
Subject(s) - medicine , d dimer , deep vein , receiver operating characteristic , thrombosis , area under the curve , gastroenterology , predictive value , predictive value of tests , neutrophil to lymphocyte ratio , lymphocyte
Patients with deep vein thrombosis (DVT) pose high morbidity and mortality risk thus needing fast and accurate diagnosis. Wells clinical prediction scores with D-dimer testing are traditionally used to rule out patients with low probability of DVT. However, D-dimer testing has a few limitations regarding its relatively low specificity. Neutrophil-lymphocyte ratio (NLR), a marker of inflammation, was found to increase in DVT. Hence, we aimed to evaluate the role of NLR for DVT diagnosis.