Open Access<p>Serum high mobility group box protein 1 (HMGB1) levels reflect clinical features of childhood hemophagocytic lymphohistiocytosis</p>
Author(s) -
Hiroshi Takahashi,
Shinji Kounami,
Takayuki Ichikawa,
Taketsugu Hama,
Hiroyuki Suzuki
Publication year - 2019
Publication title -
journal of blood medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.676
H-Index - 18
ISSN - 1179-2736
DOI - 10.2147/jbm.s216121
Subject(s) - medicine , pathogenesis , hemophagocytic lymphohistiocytosis , hmgb1 , interquartile range , gastroenterology , immunology , disease , inflammation
Hemophagocytic lymphohistiocytosis (HLH) is a potentially lethal hyperinflammatory disorder. For further understanding of the pathogenesis of HLH, we examined serum levels of high mobility group box protein 1 (HMGB1) in children with HLH.