Open AccessCircular RNA ERBB2 Contributes to Proliferation and Migration of Airway Smooth Muscle Cells via miR-98-5p/IGF1R Signaling in Asthma
Author(s) -
Junyan Huang,
Fang Wang,
Long-Tao Wang,
Yongmei Li,
Junli Lu,
Jianyou Chen
Publication year - 2021
Publication title -
journal of asthma and allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.162
H-Index - 30
ISSN - 1178-6965
DOI - 10.2147/jaa.s326058
Subject(s) - insulin like growth factor 1 receptor , platelet derived growth factor receptor , gene knockdown , growth factor , cell growth , medicine , insulin like growth factor , cancer research , microbiology and biotechnology , receptor , biology , apoptosis , biochemistry
Asthma belongs to chronic inflammatory respiratory diseases characterized by airway inflammation and remodeling. Circular RNAs (circRNAs) are promising therapeutic targets for various diseases, including asthma. In this work, we aim to investigate the role of circular RNA Erb-B2 receptor tyrosine kinase 2 (circERBB2) during progression of asthma.