Open AccessThe Usefulness of FEF25–75 in Predicting Airway Hyperresponsiveness to Mannitol
Author(s) -
Youlim Kim,
SangDo Lee,
Sung Jun Chung,
Yoomi Yeo,
Tai Sun Park,
Dong Won Park,
Kyung Hoon Min,
SangHeon Kim,
Tae-Hyung Kim,
Jang Won Sohn,
Ji-Yong Moon,
Ho Joo Yoon
Publication year - 2021
Publication title -
journal of asthma and allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.162
H-Index - 30
ISSN - 1178-6965
DOI - 10.2147/jaa.s318502
Subject(s) - medicine , spirometry , airway hyperresponsiveness , vital capacity , confidence interval , asthma , population , area under the curve , gastroenterology , lung , lung function , diffusing capacity , environmental health
Despite the usefulness of airway hyperresponsiveness (AHR) testing in diagnosing and monitoring asthma, it is challenging to perform in a real-world setting. Forced expiratory flow between 25% and 75% of vital capacity (FEF 25-75 ), a pulmonary measurement that can be obtained easily during routine spirometry, represents the status of medium-sized and small airways. However, the performance of FEF 25-75 in predicting AHR has not been well elucidated. Therefore, we investigated whether FEF 25-75 can predict AHR to mannitol.