Open AccessMuc5ac Production Inhibited by Decreased lncRNA H19 via PI3K/Akt/NF-kB in Asthma
Author(s) -
Xu Chen,
Jianqi Yang,
Hailan Shen,
Xuemei Zhang,
Hong Wang,
Guangying Wu,
Yuhong Qi,
Ling Wang,
Wenchun Xu
Publication year - 2021
Publication title -
journal of asthma and allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.162
H-Index - 30
ISSN - 1178-6965
DOI - 10.2147/jaa.s316250
Subject(s) - gene knockdown , in vitro , inflammation , pi3k/akt/mtor pathway , cancer research , medicine , protein kinase b , messenger rna , downregulation and upregulation , asthma , immunology , microbiology and biotechnology , biology , cell culture , signal transduction , gene , biochemistry , genetics
LncRNAs play important roles in multiple diseases including asthma, while there are a few reports on the role of lncRNA H19 about asthma. This study aimed to investigate the roles and mechanisms of lncRNA H19 in asthma.