Open AccessYAP Promotes Cell Proliferation and Epithelium-Derived Cytokine Expression via NF-κB Pathway in Nasal Polyps
Author(s) -
Huiyi Deng,
Meijiao Li,
Rui Zheng,
Huijun Qiu,
Yuan Tian,
Weihao Wang,
Qintai Yang,
ZiJie Long,
Xianbo Huang
Publication year - 2021
Publication title -
journal of asthma and allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.162
H-Index - 30
ISSN - 1178-6965
DOI - 10.2147/jaa.s315707
Subject(s) - thymic stromal lymphopoietin , hippo signaling pathway , cell growth , medicine , microbiology and biotechnology , cancer research , epithelium , gene knockdown , cytokine , signal transduction , immunology , apoptosis , biology , pathology , biochemistry , genetics
Hippo-Yes-associated protein (YAP) pathway plays an important role in epithelial cell proliferation and inflammation development in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the underlying mechanisms remain unclear.