Open AccessOmega-5 and Gamma Gliadin are the Major Allergens in Adult-Onset IgE-Mediated Wheat Allergy: Results from Thai Cohort with Oral Food Challenge
Author(s) -
Surapon Piboonpocanun,
Torpong Thongngarm,
Chamard Wongsa,
Punchama Pacharn,
Onrapak Reamtong,
Mongkhon Sompornrattanaphan
Publication year - 2021
Publication title -
journal of asthma and allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.162
H-Index - 30
ISSN - 1178-6965
DOI - 10.2147/jaa.s315202
Subject(s) - gliadin , glutenin , wheat allergy , medicine , food allergy , allergy , allergen , immunoglobulin e , sensitization , immunology , gluten , cohort , prolamin , anaphylaxis , storage protein , biology , antibody , biochemistry , pathology , protein subunit , gene
Various clinical patterns based on routes of sensitization and sensitized allergens are reported in adult-onset IgE-mediated wheat allergy. There is still a paucity of data on IgE-bound wheat allergen profiles in wheat challenge-proven adult-onset wheat allergic cases. Therefore, we aim to identify the major sensitized allergens in Thai adult-onset wheat allergic patients whose first symptom occurred after the age of 18 years despite previous tolerance.