Open AccessEffectiveness of Switching Biologics for Severe Asthma Patients in Japan: A Single-Center Retrospective Study
Author(s) -
Takanori Numata,
Jun Araya,
Hanae Miyagawa,
Kunio Okuda,
Yu Fujita,
Hirofumi Utsumi,
Daisuke Takekoshi,
Mitsuo Hashimoto,
Shunsuke Minagawa,
Takeo Ishikawa,
Hiromichi Hara,
Kazuyoshi Kuwano
Publication year - 2021
Publication title -
journal of asthma and allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.162
H-Index - 30
ISSN - 1178-6965
DOI - 10.2147/jaa.s311975
Subject(s) - medicine , omalizumab , exhaled nitric oxide , mepolizumab , asthma , dupilumab , retrospective cohort study , benralizumab , eosinophil , pediatrics , immunoglobulin e , immunology , spirometry , antibody
In Japan, biologic therapy was initiated for patients with severe asthma in 2009. In recent years, four biologics with different mechanisms of action have become available in the clinical setting. However, the efficacy of switching between biologics remains uncertain.