Open AccessIdentification of Risk Factors and Cross-Reactivity of Local Anesthetics Hypersensitivity: Analysis of 14-Years’ Experience
Author(s) -
İlkay Koca Kalkan,
Gözde Köycü Buhari,
Hale Ateş,
Buket Başa Akdoğan,
Özlem Özdedeoğlu,
Kurtuluş Aksu,
Ferda Öner Erkekol
Publication year - 2021
Publication title -
journal of asthma and allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.162
H-Index - 30
ISSN - 1178-6965
DOI - 10.2147/jaa.s292442
Subject(s) - medicine , allergy , drug allergy , retrospective cohort study , family history , risk factor , relative risk , cohort , dermatology , immunology , confidence interval
Local anesthetics (LA) are widely used and adverse drug reactions (ADR) occur in 2.5-10%, but hypersensitivity reactions are rare (ranging between 0% and 4.3%). Risk is so overestimated causing too many allergy clinic referrals. There are limited and also conflicting results over the management of LA allergy. We aimed to find out who should be referred to an allergy clinic for a LA allergy testing, to define the subjects with an increased risk of LA allergy and to assess the need for testing for identifying alternative LA.