Open AccessAnnual Fractional Exhaled Nitric Oxide Measurements and Exacerbations in Severe Asthma
Author(s) -
Yuki Abe,
Masaru Suzuki,
Hirokazu Kimura,
Kaoruko Shimizu,
Hironi Makita,
Masaharu Nishimura,
Satoshi Konno
Publication year - 2020
Publication title -
journal of asthma and allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.162
H-Index - 30
ISSN - 1178-6965
DOI - 10.2147/jaa.s289592
Subject(s) - medicine , exhaled nitric oxide , exacerbation , asthma , asthma exacerbations , cohort , inhaled corticosteroids , gastroenterology , pediatrics , spirometry
Fractional exhaled nitric oxide (FENO) reflects eosinophilic inflammation of the airways. However, the significance of longitudinal assessment of FENO, including its variability, in the clinical course of severe asthma remains unclear. The aim of this study is to examine the association between long-term changes in FENO and the development of exacerbations in severe asthma.