Open Access<p>Type 2 Inflammatory Biomarker Response After Exercise Challenge Testing</p>
Author(s) -
Ellen Tufvesson,
Henning Stenberg,
Jaro Ankerst,
Leif Bjermer
Publication year - 2020
Publication title -
journal of asthma and allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.162
H-Index - 30
ISSN - 1178-6965
DOI - 10.2147/jaa.s258561
Subject(s) - medicine , periostin , bronchoconstriction , asthma , biomarker , treadmill , endocrinology , immunology , biochemistry , chemistry , extracellular matrix , biology , microbiology and biotechnology
Exercise-induced bronchoconstriction is due to osmotic stimulus of the airway epithelium and leads to a cascade of biomarker release from several inflammatory cells. Several type 2 (T2) mediators have been linked to exercise-induced bronchoconstriction, but the T2 response per se has not been described during exercise. The aim of this study was therefore to investigate T2 biomarkers in plasma and urine from subjects with asthma and healthy controls before and after an exercise challenge.