Open Access<p>Latex Allergy: Current Status and Future Perspectives</p>
Author(s) -
Eleonora Nucera,
Arianna Aruanno,
Angela Rizzi,
Michele Centrone
Publication year - 2020
Publication title -
journal of asthma and allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.162
H-Index - 30
ISSN - 1178-6965
DOI - 10.2147/jaa.s242058
Subject(s) - medicine , desensitization (medicine) , epidemiology , etiology , latex allergy , hevea brasiliensis , intensive care medicine , allergy , natural history , gold standard (test) , dermatology , immunology , natural rubber , chemistry , receptor , organic chemistry
Allergy to natural rubber latex (NRLA) from Hevea brasiliensis is a relevant public health issue, in particular in healthcare workers and groups at risk. Clinical manifestations of NRLA can range from mild skin disorders to life-threatening systemic reactions. Prevention measures remain the gold-standard treatment for patients suffering from NRLA, but the only etiological therapy able to influence the natural history of NRLA is specific desensitization. This review aims to underline the epidemiological, clinical and diagnostic aspects of NRLA, and carries out a complete and wide-ranging review of the current literature on NRLA management and immunotherapy.