Open Access<p>Acetylcholine Regulates Pulmonary Pathology During Viral Infection and Recovery</p>
Author(s) -
Alexander P Horkowitz,
Ashley V. Schwartz,
Carlos Álvarez,
Edgar B Herrera,
Marilyn L. Thoman,
Dale A. Chatfield,
Kent G. Osborn,
Ralph Feuer,
Uduak Z. George,
J. C. Phillips
Publication year - 2020
Publication title -
immunotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.256
H-Index - 7
ISSN - 2253-1556
DOI - 10.2147/itt.s279228
Subject(s) - acetylcholine , inflammation , cholinergic , immune system , immunology , lung , biology , medicine , pathology , endocrinology
This study was designed to explore the role of acetylcholine (ACh) in pulmonary viral infection and recovery. Inflammatory control is critical to recovery from respiratory viral infection. ACh secreted from non-neuronal sources, including lymphocytes, plays an important, albeit underappreciated, role in regulating immune-mediated inflammation.