Open AccessIncidental Finding of Elevated Serum Cartilage Oligomeric Matrix Protein (sCOMP) in Knee Osteoarthritis Patient with Undiagnosed Colon Cancer: A Case Report
Author(s) -
Yose Waluyo,
Gita Vita Soraya,
Susanto H Kusuma,
Faradilla Anwar,
Insani Nanda Wahyuni
Publication year - 2021
Publication title -
international medical case reports journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.198
H-Index - 11
ISSN - 1179-142X
DOI - 10.2147/imcrj.s283797
Subject(s) - medicine , cartilage oligomeric matrix protein , osteoarthritis , biomarker , colorectal cancer , rheumatoid arthritis , cancer , cartilage , prolotherapy , oncology , breast cancer , arthritis , prostate cancer , pathology , biochemistry , chemistry , alternative medicine , anatomy
The clinical utility of cartilage oligomeric matrix protein (COMP) as a diagnostic and prognostic biomarker is currently under intense study. COMP has been associated primarily with musculoskeletal disorders such as rheumatoid and osteoarthritis (OA) or muscular and ligament trauma. Aside from its established role as a biomarker of arthritis, an increasing number of studies have also suggested the role of COMP in tumorigenesis, based on findings of its expression in breast, prostate, and colon cancers.