Open AccessRelationship of Placental and Serum Lipoprotein-Associated Phospholipase A2 Levels with Hypertensive Disorders of Pregnancy
Author(s) -
Jing Wang,
Xing Dong,
Hongyan Wu,
Wen-Hua Bu,
Rong Cong,
Xin Wang,
Shang Liu,
Wen Jiang
Publication year - 2022
Publication title -
international journal of women's health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.136
H-Index - 45
ISSN - 1179-1411
DOI - 10.2147/ijwh.s361859
Subject(s) - preeclampsia , medicine , endocrinology , lipoprotein associated phospholipase a2 , gestational hypertension , phospholipase a2 , pregnancy , lipoprotein , case control study , pathophysiology , placenta , enzyme , biology , cholesterol , fetus , biochemistry , genetics
A series of studies has shown that lipoprotein-associated phospholipase A2 (Lp-PLA2) is closely associated with abnormal lipid metabolism and vascular endothelial cell injury, but its role in hypertensive disorders of pregnancy (HDP) remains unclear. This study aims to determine the relationship between placental and serum LP-PLA2 levels and HDP, and to provide a feasible method for predicting HDP.