Open AccessThe Role of Diffusion-Weighted MRI and Apparent Diffusion Coefficient in Assessment of Diabetic Kidney Disease: Preliminary Experience Study
Author(s) -
Nasr Mohamed M. Osman,
Moustafa Abdel Kader,
Taghreed A E L Aziz Nasr,
Mohamed Ahmed Sharawy,
Hesham Kamal Habeeb Keryakos
Publication year - 2021
Publication title -
international journal of nephrology and renovascular disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.846
H-Index - 27
ISSN - 1178-7058
DOI - 10.2147/ijnrd.s254022
Subject(s) - medicine , kidney disease , effective diffusion coefficient , nephrology , renal function , kidney , end stage renal disease , urology , disease , magnetic resonance imaging , radiology
Diabetic kidney disease is the most common cause of ESRD. There is poor correlation between the degree of renal fibrosis and current screening markers. A noninvasive imaging technique is needed to assess the degree of structural changes in the kidney. The aim of this study was to assess the role of apparent diffusion coefficient (ADC) in the diagnosis of diabetic kidney disease. Forty adult diabetic patients with chronic kidney disease as well as 20 age- and sex-matched adult healthy controls were recruited from Nephrology Department of our University Hospital. All patients underwent renal MR-DWI and ADC mapping on a 1.5-T scanner (Philips Achieva) using phased array body coil.